BALTIMORE - J.P. Arencibia hit his first career grand slam, Rajai Davis had three hits and the Toronto Blue Jays beat the Baltimore Orioles 8-4 on Friday night to end a two-game losing streak.

Carlos Villanueva (3-0) allowed two runs and six hits in 5 1-3 innings, walking one. He is 2-0 in three starts since moving into the Toronto rotation from the bullpen.

Arencibia's fifth-inning slam was his ninth homer of the season and gave the Blue Jays a 7-0 lead against Orioles rookie Zach Britton, who has lost three straight decisions after starting the season 5-1.

Toronto has won 21-of-27 games against the Orioles and is 16-3 in its last 19.

J.J. Hardy homered for Baltimore, which has dropped six of seven games to fall five games below .500, matching a season high.

Britton (5-4) allowed seven runs -- five earned -- and six hits over five innings, his shortest outing.

Two miscues by the Orioles helped Toronto to a 2-0 lead in the second. After Juan Rivera's leadoff single, Arencibia reached on an error by third baseman Mark Reynolds. Aaron Hill singled in a run and Edwin Encarnacion grounded into a double play before Britton's wild pitch plated Arencibia.

In the third, Yunel Escobar led off with a double, went to third on Corey Patterson's sacrifice bunt and scored on Rivera's sacrifice fly.

Arencibia's slam broke the game open in the fifth. The Blue Jays loaded the bases on a walk to Escobar, a single by Jose Bautista and a walk to Rivera before Arencibia ripped Britton's 2-2 fastball into the seats in left.

Villanueva didn't allow a hit until Hardy led off the fifth with a single to centre, the first of four Baltimore hits in the inning. Hardy later scored on Robert Andino's two-out liner to left and a single by Adam Jones to make it 7-2.

Escobar's broken-bat single in the sixth scored Davis, who had doubled with one out and stole third base.

Hardy hit a two-run homer off Jason Frasor in the eighth.

NOTES: Friday night marked the first meeting of the season between the AL East rivals. ... Toronto is 14-14 on the road. ... In 12 games since being activated from the DL on May 16, Toronto 2B Jayson Nix is 5 for 32. He went 0 for 4 Friday night. ... Orioles 1B Derrek Lee, sidelined since May 15 with a strained left oblique, began an injury rehabilitation assignment with Double-A Bowie on Friday, going 2 for 3 with a walk as the designated hitter.