A serious accident shut down Highway 400 in both directions Monday afternoon.
A man was ejected from his seat and a female driver was also injured after their car spun out of control near the Highway 89 exit and rolled over a number of times.
Police shut down the highway so that a helicopter could airlift the man to Sunnybrook hospital. The woman was rushed to Royal Victoria Hospital in Barrie.
OPP Commissioner Julian Fantino said this is yet another case of a preventable accident.
"We're talking about totally preventable circumstances," he told CTV News. "People driving aggressively, losing control of vehicles. The end result is two people injured and thousands of motorists stranded."
The highway's northbound lanes were reopened but investigators kept the southbound direction down to one lane as they tried to reconstruct the accident.
The accident occurred at the same time OPP were scouring the highways on Thanksgiving weekend, searching for speeders and unsafe cars.
Operation Impact resulted in thousands of cars being clocked, weighed and pulled off the road for safety checks.
Jason Collins, with the Ministry of Transportation, said he has seen everything from balding tires to leaking brake lines.
"You do have to shake your head and you have to wonder what people are thinking," he said.
The OPP are also implementing their new anti-speed racing law which allows officers to strip drivers of their licenses for a week if they are caught going 50 km/h over the speed limit. The law also allows them to seize their car for the week.
In the week since the law came into effect, more than 300 cars have been taken off the road. By 10 a.m., police seized six cars for excessive speeding.
With a report from CTV's Mairianna Bachynsky