Police say an investigation into a collision involving a TTC bus and a truck that left one woman dead and several injured is “wide open” as they try to determine what caused the crash.

Investigators are reviewing recovered video and a data recorder, and have spoken with several witnesses after a truck struck the right front-end of a TTC bus Tuesday in Toronto’s northeast end, near the intersection of Steeles Ave. and Middlefield Rd.

A woman, identified as 52-year-old Manoranjana Kanagasabapathy, was killed when the eastbound cube van hit the curb, a light standard and the bus, police said. She had been in the process of getting on the stopped bus. She was pronounced dead at the scene.

A small makeshift memorial was placed at the crash site Wednesday as distraught relatives arrived to pay their respects.

Her grieving brother told CTV Toronto the family is devastated.

“I don’t know (why) these kind of things happen to good souls; honestly, I’m not saying because she is my sister, but I couldn’t find any better person than her,” he said.

The new grandmother came to Canada from Sri Lanka two decades ago, and lived in Scarborough. She worked in a bank near the accident scene and prayed often at a nearby temple.

Kanagasabapathy sacrificed for her family and never wanted material things, her brother said. “She was content with what she had and to lose her at this age … we can’t even comprehend.”

Twelve people in total were injured, including 11 passengers who were on the bus. They were taken to hospitals in Markham, Scarborough and Toronto.

At least one other person – a women who had just stepped off the bus – was critically injured after being struck. She is expected to survive.

Both the bus driver, 36, and the truck driver, 40, were also taken to hospital.

On Wednesday, crews also removed the hydro pole that was snapped in the crash.

Const. Clint Stibbe told CTV Toronto’s Tamara Cherry that investigators are also looking at possible contributing factors, including mechanical failure. Police are also trying to determine whether or not the truck driver was on the phone at the time of the crash, and if he was speeding, as witnesses have suggested.

Police are asking anyone with information on the collision to contact them.

Hours after the crash, Toronto Mayor Rob Ford extended his condolences to the family of the deceased victim.

"On behalf of City Council and all Toronto residents, I want to extend my deepest sympathies to the family and friends of the deceased at this difficult time,” said Mayor Ford in a statement. "I am very saddened to hear about this tragic accident."

One witness who was on the bus was visibly shaken by the crash.

"All I can remember is this impact and the glass and everything flying and I just plunged forward," Hanan Nur told CTV Toronto. "I remember screaming and everybody just running out, and I just followed because I didn't know what else to do – my knees were hurting and all I could think was get out get out the bus might explode."

Police say the investigation is expected to take up to two weeks.

Meanwhile, a funeral for Kanagasabapathy is being arranged for the weekend.

With a report from CTV Toronto’s Austin Delaney