A London, Ont., woman is dead after a major collision on Highway 10 in central Ontario.

The 66-year-old woman was a passenger in an SUV which crashed into a pickup truck just before 4 p.m. on Wednesday, north of Orangville, police said.

The driver of the SUV, a 68-year-old man, sustained serious knee and back injuries. He was rushed to hospital, along with the woman where she died from her injuries.

Police officers said no charges have been laid and an investigation of the incident is underway.

With files from The Canadian Press.