LONDON, Ont. -- Police in London, Ont., say they've made the largest seizure of fentanyl in the city's history.

They say officers with the guns and drugs unit raided a home Wednesday morning where they found 107 grams of the deadly opioid.

Police say they also found cocaine, marijuana and nearly $10,000 cash.

They say they charged one man and two women with various trafficking-related offences.

London police have been carrying the opioid antidote naloxone since June and say their officers have used it more than 55 times.

Det. Sgt. Rob Merrimen says cutting supply of illicit fentanyl is part of the effort to deal with ongoing opioid overdose crisis that has hit the country.