Police say the incident occurred near The West Mall and Rathburn Road at approximately 7 p.m. on Wednesday night.
When authorities arrived, they found a man who was without vital signs, and had "apparent stab wounds."
The victim, who was pronounced dead at the scene, has been identified by police as Saed Keyliye, 17.
Witnesses told police they saw two men fleeing the scene.
Police said surveillance video in the area showed four males climbing a fence near the crime scene.
“It appears on the video that two males are in pursuit of the other two males,” Det. Sgy. Steve Ryan told reporters.
Investigators have not provided a description of the three males sought in connection with the incident.
Anyone with information relating to the incident is being asked to contact police at 416-808-2246, or Crime Stoppers at 416-222-8477.
