A 10-year-old boy is dead and two other family members seriously injured after a house fire in Scarborough, Ont., early Saturday morning.

Neighbours have identified the boy who died as Mark Mrochuk, the eldest son in a family of six people.

Police, paramedics and firefighters responded to the blaze in a townhouse complex on Kingston Road just before 6 a.m.

A man, a woman and four children were inside the house at the time of the fire, firefighters said.

Firefighters initially got only two children out, but went back in and managed to retrieve the mother and other two children.

All four children and their mother were taken to hospital. A boy, 10, later succumbed to his injuries, Toronto Police said.

The mother and a female child remain in serious condition, and are being treated at Scarborough General Hospital and Sick Kids respectively. The father and two other children have non-life threatening injuries.

A paramedic told CTV Toronto that mother was originally found without vital signs, but was resuscitated.

“She’s still got a tough battle ahead of her,” the paramedic said.

The father managed to get out of the home unharmed, but tried to go back in, according to neighbour Donna Sancho, who was awakened by the smell of smoke.

“The father was really distraught so they had to literally handcuff him and stop him from going back into the house,” she said.

"No one could get into the house," Sancho added. "Fire was orange and black with smoke, everyone was trapped."

Firefighters said the fire probably began in the second floor kitchen and spread into the home’s dining room. The family was most likely asleep when the fire broke out.

Toronto Community Housing (TCHC) issued a statement Saturday, saying initial reports seemed to show that fire alarms in the unit were working.

"The system in this home was fully functional at the last inspection in December 2014," the statement said.

TCHC also offered condolences to the family.

Jeff Tebby, an investigator with the Office of The Ontario Fire Marshal, said the fire did not spread to any nearby homes and there is no concern about other structures.

“We are fortunate it did not spread,” he added.

Tebby encouraged families to develop an “escape plan.”

He said there was “nothing suspicious” about the blaze.

Meanwhile, a makeshift memorial grew outside the housing complex Saturday afternoon, as people dropped off flowers for the young victim.

Classmates from Eastview Public School who showed up to pay their respects said Mark was a nice boy who enjoyed playing hockey.

Several crowdfunding campaigns have been set up to help cover the family's expenses and the cost of Mark's funeral.

With a report form CTV Toronto’s Janice Golding